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Southwestern Spice-Rubbed Bison Tenderloin

Yield 8 servings (serving size: 3 ounces)
Bison (sometimes labeled buffalo) tenderloin is a lean cut, so cook it quickly at moderately high heat to ensure it stays juicy and tender. We prefer it rare, but adjust the cook time to suit your preference. Chateaubriand-cut refers to the center-cut portion of the tenderloin, so the roast is a uniform thickness throughout. If your local butchers don't stock bison meat, try online sources like or www.highplainsbison?.com—or substitute beef tenderloin.


  • 1 tablespoon canola oil
  • 1 1/2 teaspoons ancho chile powder
  • 1 teaspoon ground cumin
  • 1 teaspoon dark brown sugar
  • 1/2 teaspoon salt
  • 1/2 teaspoon dried oregano
  • 1/2 teaspoon freshly ground black pepper
  • 1/4 teaspoon garlic powder
  • 1/4 teaspoon celery seeds
  • 1 (2-pound) chateaubriand-cut bison tenderloin
  • 1 tablespoon fresh lime juice
  • Cooking spray

Nutrition Information

  • calories 144
  • caloriesfromfat 25 %
  • fat 4 g
  • satfat 0.9 g
  • monofat 1.9 g
  • polyfat 0.8 g
  • protein 24.4 g
  • carbohydrate 1.3 g
  • fiber 0.4 g
  • cholesterol 70 mg
  • iron 3.2 mg
  • sodium 202 mg
  • calcium 14 mg

How to Make It

  1. Combine first 9 ingredients in a small bowl. Place bison on a dish; drizzle with juice. Rub spice mixture over bison. Cover and refrigerate 1 hour.

  2. Preheat oven to 425°.

  3. Let bison stand at room temperature 15 minutes. Secure bison at 2-inch intervals with twine.

  4. Place bison in a small roasting pan coated with cooking spray. Bake at 425° for 25 minutes or until a thermometer registers 115° or until desired degree of doneness (temperature will continue to rise as roast stands). Remove from oven; let stand 20 minutes before slicing.