1. Place shanks, wine, and 1 cup water in a large saucepan over medium-high heat. Boil 5 minutes or until liquid is reduced by one-third.
2. Melt butter in large skillet over medium heat until butter is foamy. Transfer shanks to skillet, reserving wine mixture, and reduce heat to low. Cook shanks 10 minutes, turning once, until meat is browned.
3. Remove shanks from skillet, and place in slow cooker; sprinkle shanks evenly with 1 teaspoon salt. Deglaze skillet by adding reserved wine mixture and stirring to loosen particles from pan.
4. Pour wine mixture over meat; add pearl onions and next 8 ingredients. Season with pepper and remaining 1 teaspoon salt. Cook on HIGH for 4 to 5 hours or until tender.
Note: To blanch is to plunge briefly into boiling water, then into cold water to stop the cooking process.