Preheat oven to 375°. Combine first 12 ingredients in a large bowl, and stir well. Crumble beef over vegetable mixture, and stir just until blended.
Pack mixture into a 9 x 5-inch loaf pan coated with cooking spray. Bake at 375° for 1 hour or until meat loaf registers 160°. Let meat loaf stand in pan 10 minutes.
Remove meat loaf from pan; cut loaf into 16 slices. Serve with commercial salsa, if desired.
Sandwich suggestion: Serve leftover meat loaf slices in taco shells; top with shredded lettuce, chopped tomato, and shredded cheese.
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