Working with 1 biscuit at a time (cover remaining biscuits to keep from drying), pat each biscuit into a 3-inch circle. Spoon about 1 teaspoon cream cheese mixture into center of each circle; gather dough over filling to form a ball, pinching seam to seal.
Place filled biscuits, seam sides up, in a 13 x 9-inch baking pan coated with cooking spray. Drizzle butter over biscuits; sprinkle with brown sugar.
Bake at 350° for 40 minutes or until lightly browned.