Heat 2 Tbsp. bacon drippings in a deep saucepan over medium until melted. Remove from heat; slowly stir in 2 cups (16 oz.) vodka until drippings are evenly incorporated. Cool completely, about 30 minutes.
Pour mixture into a wide-mouth jar or glass measuring cup; cover and chill 8 hours or overnight.
Skim fat from surface of vodka; discard fat. Line a fine wire-mesh strainer with 2 layers of cheesecloth. Pour vodka through prepared strainer into a clean glass jar; discard solids. Repeat process until vodka is clear of any particles. Cover and store in refrigerator up to 2 weeks.