1. In a slow cooker, place onion, peppers, mushrooms and chuck roast.
2. In a small bowl, combine basil, oregano, thyme, garlic and pepper; evenly sprinkle over meat.
3. In a medium bowl, add water, wine, vinegar and Roasted Beef Base; stir until base dissolves and pour over meat.
4. Cover and cook on low for 8 hours or until meat is fork tender.
5. Place meat in bowl with broth. Serve with Italian bread and shredded cheese.