Combine flour and baking powder in a large mixing bowl, stirring well. Cut in shortening with a pastry blender until the mixture resembles coarse meal. Gradually add buttermilk, stirring until dry ingredients are moistened.
Turn dough out onto a floured surface, and knead 4 to 5 times.
Roll dough to 1/2-inch thickness; cut with a 2 3/4-inch biscuit cutter. Place biscuits on a greased baking sheet. Bake at 425° for 12 minutes or until biscuits are lightly browned.