Trim rind from top of Brie, leaving a 1/2" border. Place Brie on a microwave-safe plate.
Combine cranberries, pecans, and sugar; sprinkle over Brie. Drizzle with honey. Cover and chill until ready to heat.
Microwave at HIGH 1 1/2 to 2 minutes or just until cheese is softened. Serve with crackers and pear slices.
For Entertaining: If you can't find a 2-pound wheel of Brie, buy 4 (8-ounce) rounds of Brie. Divide the topping evenly among the 4 rounds and microwave, 2 at a time, at HIGH 1 1/2 minutes. For an interesting presentation, stack the Brie on a serving tray.